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Pathway name Pathway source Gene number Edge number Geneset
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants reactome 57 500 ADAM10;ADAM17;APH1A;APH1B;CCNC;CDK8;CREBBP;CUL1;DLL1;DLL4;EP300;FBXW7;HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;HES1;HES5;HEY1;HEY2;HEYL;JAG1;JAG2;KAT2A;KAT2B;MAML1;MAML2;MAML3;MAMLD1;MIB1;MIB2;MYC;NCOR1;NCOR2;NCSTN;NEURL1;NEURL1B;NOTCH1;PSEN2;PSENEN;RBPJ;RBX1;RPS27A;SKP1;SNW1;TBL1X;TBL1XR1;UBA52;UBB;UBC

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants